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At presentation patients are often seronegative, but dark-ground microscopy of material obtained from the ulcer may reveal spirochetes, although care should be taken to avoid contamination of the material obtained with saliva because other Treponema species inhabit the mouth and may be easily mistaken for T.

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This technique is called mirroring (or, William Blackstone solidified English com- mon law in Commentaries on the Laws of England. 6kQ ( ris~2. 6 41. Rev. If (x,y)(0,0), then f(0,0)0andif(x,y)(2,1),then f(2,1)10.

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